Company Mission & Profile

22nd Century is a plant biotechnology company with an important mission: To Reduce the Harm Caused by Smoking.

Our proprietary genetic engineering technology and plant breeding expertise allow us to regulate the level of nicotine (and other nicotinic alkaloids) in the tobacco plant. As a result of our unique technology, we are able to grow tobacco with up to 97% less nicotine than conventional tobacco – as well as plants with relatively high nicotine levels. The applications for this technology are extraordinary; in independent clinical studies, our very low nicotine (VLN) tobacco has demonstrated remarkable efficacy as a smoking cessation aid. On the other hand, for smokers who do not wish to quit, our high nicotine tobacco enables us to produce a cigarette with what we believe is the world’s lowest tar-to-nicotine ratio.

Protecting our technology are more than 185 issued patents and more than an additional 54 pending patent applications around the world.

Goodrich Tobacco Company, LLC, Botanical Genetics, Nasco Products, LLC, and Hercules Pharmaceuticals, LLC are wholly-owned subsidiaries of 22nd Century Group.

XXII Stock Quote


Landmark Study on Very Low Nicotine Cigarettes

Randomized Trial of Reduced-Nicotine Standards for Cigarettes
– Eric C. Donny, Ph.D., et. al.

Randomized Trial of Reduced-Nicotine Standards for Cigarettes (Key Points Video)

Reduced-Nicotine Cigarettes — A Promising Regulatory Pathway
– Michael Fiore, M.D., M.P.H., M.B.A., and Timothy Baker, Ph.D.


Video: Tobacco Regulatory Science in Action
(Stephen Higgins, Ph.D.)

Video: Tobacco Regulatory Science in Action
(Eric Donny, Ph.D.)

2014 Annual Report


Download 2014 Annual Report (PDF)