As the only company in the world capable of producing very low nicotine tobacco products, 22nd Century was chosen by the National Institute on Drug Abuse (NIDA) to supply its proprietary cigarettes as a subcontractor under a federal government contract. The main SPECTRUM® product line consists of a series of cigarette styles that have a fixed “tar” yield but varying nicotine yields over a 50-fold range – from very low to high. Altogether, SPECTRUM® features 24 styles, 11 regular and 13 menthol versions, with 8 different levels of nicotine content. SPECTRUM® is strictly for research purposes and is not sold as a commercial cigarette.

To date, 22nd Century has delivered over 22 million SPECTRUM® research cigarettes for the National Institute on Drug Abuse.

Without SPECTRUM® cigarettes, many important research projects investigating the exposure and behavioral effects of different nicotine levels in cigarettes would simply be impossible to conduct. Most recently, SPECTRUM® cigarettes were an integral part of the study conducted by Eric C. Donny, Ph.D., et al and the Center for the Evaluation of Nicotine in Cigarettes and published in The New England Journal of Medicine (N Engl J Med 2015; 373:1340-1349).

22nd Century receives many requests, including from parties in various countries around the world, for cigarettes with varying nicotine levels. 22nd Century only supplies SPECTRUM® to RTI, however, the Company can supply other tobacco cigarettes with specific nicotine content levels (from very low, approximately 0.50 mg/g to high, approximately 50 mg/g) to other researchers. If you are an accredited research organization interested in learning more about research cigarettes, please click on “Contact Us” and a Company representative will respond to your inquiry. For immediate assistance, please telephone the Company.